Strategies to establish the link between biosynthetic gene clusters and secondary metabolites
نویسندگان
چکیده
منابع مشابه
IMG-ABC: A Knowledge Base To Fuel Discovery of Biosynthetic Gene Clusters and Novel Secondary Metabolites
UNLABELLED In the discovery of secondary metabolites, analysis of sequence data is a promising exploration path that remains largely underutilized due to the lack of computational platforms that enable such a systematic approach on a large scale. In this work, we present IMG-ABC (https://img.jgi.doe.gov/abc), an atlas of biosynthetic gene clusters within the Integrated Microbial Genomes (IMG) s...
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15 صفحه اولDoBISCUIT: a database of secondary metabolite biosynthetic gene clusters
This article introduces DoBISCUIT (Database of BIoSynthesis clusters CUrated and InTegrated, http://www.bio.nite.go.jp/pks/), a literature-based, manually curated database of gene clusters for secondary metabolite biosynthesis. Bacterial secondary metabolites often show pharmacologically important activities and can serve as lead compounds and/or candidates for drug development. Biosynthesis of...
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ژورنال
عنوان ژورنال: Fungal Genetics and Biology
سال: 2019
ISSN: 1087-1845
DOI: 10.1016/j.fgb.2019.06.001